The Biological Consequences of Socioeconomic Inequalities

“The Biological Consequences of Socioeconomic Inequalities is a very timely book by an interdisciplinary group of experts that presents compelling new information about the neurobiological and systemic health consequences of socioeconomic inequalities, and it discusses some encouraging approaches for intervention using biomarkers for assessment. The emphasis on biomarkers is particularly important for demonstrating how the social environment of inequality ‘gets under the skin’ and presents both a challenge and an opportunity for this important field.”
—Bruce S. McEwen, The Rockefeller University

“The usual paradigm is to consider that socioeconomic status, environmental and genetic factors all affect a person’s health, but this book broadens that paradigm by examining also how socioeconomic and environmental factors directly affect the expression of genes and specific biological processes that themselves affect health and disease. In short, while others have shown that income affects health and health affects income, The Biological Consequences of Socioeconomic Inequalities examines the mechanisms through which income affects biological processes that affect health and cognition. This interdisciplinary book provides essential reading for researchers in the social and biological sciences interested in the income-health gradient, lays a useful foundation for the new field of individually customized medicine, and improves our understanding of how behaviors, stress, and cognitive-emotional processes lead to variation in biological functioning and disease.”
—Randall P. Ellis, Boston University, and past president, American Society of Health Economist

Social scientists have repeatedly uncovered a disturbing feature of economic inequality: people with larger incomes and better education tend to lead longer, healthier lives. This pattern holds across all ages and for virtually all measures of health, apparently indicating a biological dimension of inequality. But scholars have only begun to understand the complex mechanisms that drive this disparity. How exactly do financial well-being and human physiology interact? The Biological Consequences of Socioeconomic Inequalities incorporates insights from the social and biological sciences to quantify the biology of disadvantage and to assess how poverty gets under the skin to impact health.

Drawing from unusually rich datasets of biomarkers, brain scans, and socioeconomic measures, Biological Consequences of Socioeconomic Inequalities illustrates exciting new paths to understanding social inequalities in health. Barbara Wolfe, William N. Evans and Nancy Adler begin the volume with a critical evaluation of the literature on income and health, providing a lucid review of the difficulties of establishing clear causal pathways between the two variables. In their chapter, Arun S. Karlamangla, Tara L. Gruenewald, and Teresa E. Seeman outline the potential of biomarkers—such as cholesterol, heart pressure, and C-reactive protein—to assess and indicate the factors underlying health. Edith Chen, Hannah M. C. Schreier, and Meanne Chan reveal the empirical power of biomarkers by examining asthma, a condition steeply correlated with socioeconomic status. Their analysis shows how stress at the individual, family, and neighborhood levels can increase the incidence of asthma. The volume then turns to cognitive neuroscience, using biomarkers in a new way to examine the impact of poverty on brain development. Jamie Hanson, Nicole Hair, Amitabh Chandra, Ed Moss, Jay Bhattacharya, Seth D. Pollack, and Barbara Wolfe use a longitudinal Magnetic Resonance Imaging (MRI) study of children between the ages of four and eighteen to study the link between poverty and limited cognition among children. Michelle C. Carlson, Christopher L. Seplaki, and Teresa E. Seeman also focus on brain development to examine the role of socioeconomic status in cognitive decline among older adults.

Featuring insights from the biological and social sciences, Biological Consequences of Socioeconomic Inequalities will be an essential resource for scholars interested in socioeconomic disparities and the biological imprint that material deprivation leaves on the human body.

BARBARA WOLFE is professor of public affairs, economics, and population health sciences at the University of Wisconsin-Madison.

WILLIAM N. EVANS is Keough-Hesburge Professor of Economics in the Department of Economics at the University of Notre Dame.

TERESA E. SEEMAN is professor of medicine and epidemiology in the school of public health at the University of California, Los Angeles.

CONTRIBUTORS: Nancy Adler, Jay Bhattacharya, Michelle C. Carlson, Meanne Chan, Amitabh Chandra, Edith Chen, William H. Dow, William Evans, Elliot Friedman, Tara L. Gruenewald, Daniel A. Hackman, Nicole Hair, Jamie Hanson, Arun S. Karlamangla, Catarine Kiefe, Ed Moss, Seth D. Pollak, David H. Rehkopf, Hannah M. C. Schreier, Teresa E. Seeman, Christopher L. Seplaki, Barbara Wolfe